NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in every living cell, playing a pivotal role in energy production and cellular repair. It supports mitochondrial function, enhances fat metabolism, and promotes fat loss by improving cellular efficiency. As we age, NAD+ levels naturally decline, leading to slower metabolism, decreased energy, and a higher propensity for fat accumulation. Supplementing with NAD+ helps revitalize mitochondrial health, boosts metabolic function, and aids in the repair of damaged cells, enhancing fat oxidation, improving endurance, and promoting overall anti-aging benefits. Additionally, NAD+ supports better insulin sensitivity, which can further contribute to improved body composition and fat loss.
In the human body, NAD+ works by serving as a substrate for enzymes called sirtuins and PARPs, which regulate processes like stress response, inflammation control, and genomic stability. By activating these pathways, NAD+ helps repair damaged DNA, improve mitochondrial efficiency, and support healthy cellular signaling. This makes NAD+ crucial not only for energy metabolism but also for longevity and protection against age-related decline. Its role in maintaining cellular homeostasis and promoting optimal function has positioned NAD+ as a key target in research on anti-aging, neuroprotection, and metabolic health.
Reconstitution Protocol
- Diluent/Amount: 5 mL Bacteriostatic Water (“No Sting” water suggested)
Dosage Instructions
- Dosage Range: 5mg -25mg (5 units-25units)
- Dosage Frequency: 3x a week. (M,W,F)
- Route: Subcutaneous
- Cycle Duration: Take a total of 1,000mg, then 4 week break.
- Est. Bottles needed to complete Cycle: 2 bottles.
Notes & Precautions
- Subcutaneous stomach injections or intramuscular
- As your dose increases, you may feel a tingling sensation, this is normal, but not necessary, lower dose undesirable
- Start at 5mg/dose titrate by 5mg/dose up to desired dose
- Injection may irritate at injection site or become red- this will subside.
Peptides to Stack with NAD+
- Retatrutide: A GLP-1/GIP/Glucagon triple agonist, Retatrutide helps improve insulin sensitivity, reduces appetite, and enhances fat loss, making it a powerful complement to NAD+ for boosting fat-burning and metabolic function.
- AOD-9604: A modified HGH fragment that stimulates lipolysis (fat breakdown) and helps decrease fat accumulation, working synergistically with NAD+ to optimize fat loss while preserving lean muscle mass.
- L-Carnitine: Facilitates the transport of fatty acids into the mitochondria for fat burning, improving exercise performance and fat loss, complementing NAD+ by enhancing mitochondrial energy production.
- 5-Amino-1MQ: Inhibits NNMT, leading to increased metabolic rate and enhanced fat oxidation, stacking well with NAD+ for optimized fat burning and improved body composition.